Endotherm Dokumente

 2018

Patente

US 9,994,508 B2

VERSATILE AND FUNCTIONALIZED INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND NOVEL VITAMIN D DERIVATIVES (US-Patent)

Sonstiges
3rd Compass to Europe´s Innovative Chemical Companies
Endotherm Unternehmenspräsentation

 2017

Publikationen

Mohamed, B. A., Kattner, L., Guan, K., Lehnart, S. E., Luther, S., Sossalla,S., et  al.: The relevant role of SR Ca leak in the development of heart failure.   European  Journal of Heart Failure 2017; 19(Suppl_1): 343-343.

 

Kattner L, Bernardi D: An Efficient Synthesis of 1alpha,25-Dihydroxyvitamin D3 LC-Biotin. J Steroid Biochem Mol Biol. 2017;173:89-92.

 

Kattner L, Volmer DA: Synthesis of Low Abundant Vitamin D Metabolites and Assaying Their Distribution in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) as a New Tool for Diagnosis and Risk Prediction of Vitamin D related Diseases In: A Critical Evaluation of Vitamin D - Basic Overview, Sivakumar Gowder (editor), Intech publishers, Rijeka. 2017;103-127. ISBN 978-953-51-3084-0.

Auszeichnungen
GHP International Life Sciences Award
Sonstiges
Short Company Presentation

Flyer: Your partner for vitamin D synthesis  

 2016

Publikationen
Kattner L, Rauch E: Optimization of Chemical Syntheses of Vitamin D C3-Epimers. Anticancer Res 36(3):1417-1422, 2016.
Poster: 19th Vitamin D Workshop, Boston: An Efficient Synthesis of 1,25-Dihydroxyvitamin D3 LC-Biotin
Auszeichnungen
International Life Sciences Award
Sonstiges
2nd Compass to Europe´s Innovative Chemical Companies

 2015

Publikationen
Kattner L, Bernardi D, Rauch E: Development of Efficient Chemical Syntheses of Vitamin D Degradation Products. Anticancer Res 35(2):1205-1210, 2015.
Poster, Symposium “Biological Effects of Light”, Homburg: Optimization of Chemical Syntheses of Vitamin D C3-Epimers

 

Patentanmeldungen
VERSATILE AND FUNCTIONALIZED INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND NOVEL VITAMIN D DERIVATIVES (Europäische Patentanmeldung)
VERSATILE AND FUNCTIONALIZED INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND NOVEL VITAMIN D DERIVATIVES (US-Patentanmeldung)

 2014

Publikationen
Azimi Hashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF: Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications (5):1-12, 2014.
Patentanmeldung
VERSATILE AND FUNCTIONALIZED INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND NOVEL VITAMIN D DERIVATIVES WO 2014 / 091046 A1
Vortrag
Workshop: Vitamin D analogues in cancer prevention and therapy, Krefeld: Development of Efficient Chemical Syntheses of Vitamin D Degradation Products

 2013

Publikationen
Sotoud H, Gribbon P, Ellinger B, Reinshagen J, Boknik P, Kattner L, El-Armouche A, Eschenhagen Th: Development of a Colorimetric and a Fluorescence Phosphatase-Inhibitor Assay Suitable for Drug Discovery Approaches. J Biomol Screen 18(8):899-909, 2013.
Bourgonje VJ, Vos MA, Ozdemir S, Doisne N, Acsai K, Varro A, Sztojkov-Ivanov A, Zupko I, Rauch E, Kattner L, Bito V, Houtman M, van der Nagel R, Beekman JD, van Veen TA, Sipido K, Antoons G: Combined Na+/Ca2+ Exchanger and L-Type CalciumChannel Block as a Potential Strategy to Suppress Arrhythmias and Maintain Ventricular Function. Circulation: Arrhythm Electrophysiol. 6:371-379, 2013.
Scholz T, Heyl CL, Bernardi D, Zimmermann S, Kattner L, Klein CD: Chemical, Biochemical and Microbiological Properties of a Brominated Nitrovinylfuran with Broad-Spectrum Antibacterial Activity. Bioorg Med Chem, 21:795-804, 2013.
Patent
Intermedios versátiles y funcionalizados en la síntesis de vitamina D y nuevos derivados de ES-2396524_B2

 2012

Publikationen
Poster EUTrigTreat

 2011

Publikationen
Poster, Workshop on Vitamin D, Homburg: Development of commercially applicable syntheses of Vitamin D derivatives
Vortrag
Biotechnologietage München: „Neue Therapieformen: Welche Innovationen und Trends sind zukunftsweisend und –fähig

 2010

Publikationen
Poster EUGeneHeart

 2009

Publikationen
Steuer Ch, Heinonen KH, Kattner L, Klein CD: Optimization of assay Conditions for Dengue Virus protease. Effect of various Polyols and Nonionic Detergents. J Biomol Screen. 14(9):1102-1108, 2009.
Poster “Frontiers in Medicinal Chemistry”, Heidelberg: Identification of Lead Compounds for Dengue NS3 Protease Inhibitors
Sotoud H, Kattner L, Eschenhagen Th, El-Armouche A
Colorimetric protein phosphatase inhibition assay for specific detection of phosphatase-inhibitor-1 inhibitory compounds Archiv für Experimentelle Pathologie und Pharmakologie 2009
Auszeichnungen
Nominiert für Oskar-Patzelt-Preis

 2008

Publikationen
Holzer M, Ziegler S, Albrecht B, Kronenberger B, Kaul A, Bartenschlager R, Kattner L, Klein CD, Hartmann RW: Identification of Terfenadine as an Inhibitor of Human CD81-receptor HCV-E2 Interaction: Synthesis and Structure Optimization. Molecules.13:1081-1110, 2008.       
Auszeichnungen
Nominiert für Oskar-Patzelt-Preis

 2007

Publikationen
Outsourcing of medicinal chemistry in the drug discovery process faces CRO´s and pharmaceutical companies with challenges
PharmChem. 2007, July/August, 6-7
Auszeichnungen
Preis als “Innovativstes Mitteslständisches Unternehmen des Saarlandes
Nominiert für Oskar-Patzelt-Preis